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chladič Podrobně Extrémní kappa opioid receptors signalling ulice Mimo dvanáct

Elucidating the active δ-opioid receptor crystal structure with peptide and  small-molecule agonists | Science Advances
Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists | Science Advances

Hot topics in opioid pharmacology: mixed and biased opioids - British  Journal of Anaesthesia
Hot topics in opioid pharmacology: mixed and biased opioids - British Journal of Anaesthesia

Discovery of μ,δ-Opioid Receptor Dual-Biased Agonists That Overcome the  Limitation of Prior Biased Agonists | ACS Pharmacology & Translational  Science
Discovery of μ,δ-Opioid Receptor Dual-Biased Agonists That Overcome the Limitation of Prior Biased Agonists | ACS Pharmacology & Translational Science

Pharmaceuticals | Free Full-Text | Myocardial Opioid Receptors in  Conditioning and Cytoprotection
Pharmaceuticals | Free Full-Text | Myocardial Opioid Receptors in Conditioning and Cytoprotection

Mu opioid receptor activation enhances regulator of G protein signaling 4  association with the mu opioid receptor/G protein complex in a  GTP‐dependent manner - Santhappan - 2015 - Journal of Neurochemistry -  Wiley Online Library
Mu opioid receptor activation enhances regulator of G protein signaling 4 association with the mu opioid receptor/G protein complex in a GTP‐dependent manner - Santhappan - 2015 - Journal of Neurochemistry - Wiley Online Library

Convergent, functionally independent signaling by mu and delta opioid  receptors in hippocampal parvalbumin interneurons | eLife
Convergent, functionally independent signaling by mu and delta opioid receptors in hippocampal parvalbumin interneurons | eLife

Frontiers | Regulator of G-Protein Signaling (RGS) Protein Modulation of Opioid  Receptor Signaling as a Potential Target for Pain Management
Frontiers | Regulator of G-Protein Signaling (RGS) Protein Modulation of Opioid Receptor Signaling as a Potential Target for Pain Management

Dopaminergic cellular and circuit contributions to kappa opioid receptor  mediated aversion
Dopaminergic cellular and circuit contributions to kappa opioid receptor mediated aversion

Enhancing Remyelination through a Novel Opioid-Receptor Pathway | Journal  of Neuroscience
Enhancing Remyelination through a Novel Opioid-Receptor Pathway | Journal of Neuroscience

Frontiers | A Review of the Therapeutic Potential of Recently Developed G  Protein-Biased Kappa Agonists
Frontiers | A Review of the Therapeutic Potential of Recently Developed G Protein-Biased Kappa Agonists

Frontiers | Advances in Achieving Opioid Analgesia Without Side Effects
Frontiers | Advances in Achieving Opioid Analgesia Without Side Effects

The G protein-first activation mechanism of opioid receptors by Gi protein  and agonists | QRB Discovery | Cambridge Core
The G protein-first activation mechanism of opioid receptors by Gi protein and agonists | QRB Discovery | Cambridge Core

Molecular Mechanisms of Opioid Receptor-dependent Signaling and Behavior
Molecular Mechanisms of Opioid Receptor-dependent Signaling and Behavior

Kappa opioid receptor signaling in the brain: Circuitry and implications  for treatment - ScienceDirect
Kappa opioid receptor signaling in the brain: Circuitry and implications for treatment - ScienceDirect

Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands:  Toward in Vitro Models of in Vivo Responses | ACS Chemical Neuroscience
Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands: Toward in Vitro Models of in Vivo Responses | ACS Chemical Neuroscience

Physiology, signaling, and pharmacology of opioid receptors and their  ligands in the gastrointestinal tract: current concepts and future  perspectives | SpringerLink
Physiology, signaling, and pharmacology of opioid receptors and their ligands in the gastrointestinal tract: current concepts and future perspectives | SpringerLink

Opioid receptors: drivers to addiction? | Nature Reviews Neuroscience
Opioid receptors: drivers to addiction? | Nature Reviews Neuroscience

Targeting the Kappa Opioid Receptor to Reduce Drug Use and Relapse |  National Institute on Drug Abuse (NIDA)
Targeting the Kappa Opioid Receptor to Reduce Drug Use and Relapse | National Institute on Drug Abuse (NIDA)

Regulation of opioid receptor signalling: Implications for the development  of analgesic tolerance | Molecular Brain | Full Text
Regulation of opioid receptor signalling: Implications for the development of analgesic tolerance | Molecular Brain | Full Text

Topical administration of the kappa opioid receptor agonist nalfurafine  suppresses corneal neovascularization and inflammation | Scientific Reports
Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation | Scientific Reports

Diverse Kappa Opioid Receptor Agonists: Relationships Between Signaling and  Behavior
Diverse Kappa Opioid Receptor Agonists: Relationships Between Signaling and Behavior

Dynorphin/Kappa Opioid Receptor Signaling in Preclinical Models of Alcohol,  Drug, and Food Addiction - ScienceDirect
Dynorphin/Kappa Opioid Receptor Signaling in Preclinical Models of Alcohol, Drug, and Food Addiction - ScienceDirect

Molecular mechanisms of opioid tolerance: From opioid receptors to  inflammatory mediators (Review)
Molecular mechanisms of opioid tolerance: From opioid receptors to inflammatory mediators (Review)